TIMTEC-BB SBB005581 - Names and Identifiers
TIMTEC-BB SBB005581 - Physico-chemical Properties
Molecular Formula | C7H7Br2NO
|
Molar Mass | 280.94 |
Melting Point | 205 °C |
Boling Point | 249.1°C at 760 mmHg |
Flash Point | 104.5°C |
Vapor Presure | 0.0233mmHg at 25°C |
Appearance | Solid |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
TIMTEC-BB SBB005581 - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R36 - Irritating to the eyes
R22 - Harmful if swallowed
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
Hazard Note | Irritant |
TIMTEC-BB SBB005581 - Introduction
2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide is an organic compound with the chemical formula C8H8BrNO2.
Nature:
2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide is a white crystalline solid. It is soluble in water and organic solvents at room temperature. It is stable, but may decompose when exposed to high temperatures, strong oxidants or strong acids.
Use:
2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide is a commonly used organic synthesis intermediate. It can be used in the synthesis of pyrrole derivatives, imidazoles and other organic chemical reactions.
Method:
The preparation of 2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide is usually obtained by the reaction of pyridine and bromoacetic acid. The specific preparation steps are as follows:
1. Slowly add pyridine to glacial acetic acid under cooling.
2. Bromoacetic acid was slowly added to the above reaction system, and the reaction mixture was heated.
3. After the completion of the reaction, the solution was concentrated sulfuric acid extraction.
4. The concentrated sulfuric acid transparent liquid is washed and concentrated to finally obtain 2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide.
Safety Information:
2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide has no obvious acute toxicity under normal use conditions. However, it is an organic acid and may have an irritating effect on the skin, eyes and respiratory system. Care should be taken to avoid contact with skin and eyes, and appropriate protective measures should be taken during operation, such as wearing gloves, goggles and protective clothing. Pay attention to ventilation during use and avoid reaction with strong oxidants or strong acids. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
Last Update:2024-04-10 22:29:15